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Genhong Cheng

from Calabasas, CA
Age ~56

Genhong Cheng Phones & Addresses

  • 3600 Ganelon Dr, Calabasas, CA 91302 (818) 223-3258
  • Cambridge, MA
  • Los Angeles, CA
  • 3600 Ganelon Dr, Calabasas, CA 91302 (818) 913-8812

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Publications

Us Patents

Polymer Nanofilm Coatings

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US Patent:
8263104, Sep 11, 2012
Filed:
Jun 9, 2008
Appl. No.:
12/135640
Inventors:
Dean Ho - Chicago IL,
Mark Chen - Chicago IL,
Erik Pierstorff - Highland Park IL,
Houjin Huang - Evanston IL,
Edward K Chow - Rancho Palos Verdes CA,
Genhong Cheng - Calabasas CA,
Assignee:
Northwestern University - Evanston IL
The Regents of the University of California - Oakland CA
International Classification:
A61F 2/02
A61K 31/56
US Classification:
424423, 514178
Abstract:
Disclosed herein are nanofilm coatings for implantable medical devices comprising a diblock or triblock copolymer (PEO-PMMA or PMOXA-PDMS-PMOXA, respectively). Such nanofilms, may be used, for example, as amphiphilic supports for therapeutic agents. These materials are conducive towards the formation of active substrates for a suite of biological and medical applications.

Truncated Crafi Inhibits Cd40 Signaling

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US Patent:
2002003, Mar 14, 2002
Filed:
Mar 10, 1997
Appl. No.:
08/813323
Inventors:
DAVID BALTIMORE - BOSTON MA,
GENHONG CHENG - LOS ANGELES CA,
SETH LEDERMAN - NEW YORK NY,
AILEEN CLEARY - NEW YORK NY,
International Classification:
G01N033/53
G01N033/567
G01N033/574
C12P031/00
C12P029/00
A61K039/00
C07K005/00
C07K007/00
C07K016/00
C07K017/00
A61K038/00
C07K001/00
C07K014/00
A61K038/16
US Classification:
424/185100, 530/324000, 530/350000, 530/358000, 435/007200, 435/007230, 435/063000, 435/064000
Abstract:
Overexpression of a CRAF1 (CD40 receptor-associated factor 1) gene truncated by 323 to about 414 amino acids at the amino inhibits CD40-mediated cell activation, and is used to treat conditions characterized by an unwanted level of CD40-mediated intracellular signaling.

Methods For Stimulating Tlr Irf3 Pathways For Inducing Anti-Microbial, Anti-Inflammatory And Anticancer Responses

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US Patent:
2006005, Mar 16, 2006
Filed:
Apr 24, 2003
Appl. No.:
10/512124
Inventors:
Genhong Cheng - Calabasas CA,
Robert Modlin - Sherman Oaks CA,
Sagar Vaidya - Yucca Valley CA,
Sean Doyle - Los Angeles CA,
Assignee:
THE Regents of the University of California Office of the President - Oakland CA
International Classification:
A61K 48/00
A61K 38/21
A61K 39/00
A61K 31/739
A61K 31/4745
A61K 31/337
US Classification:
424085400, 514054000, 514044000, 424185100, 514291000, 514449000
Abstract:
The present invention provides methods for stimulating Toll-like receptors (TLR) to activate IRF (e.g., an IRF3) and signaling pathway, and thereby directing an antimicrobial activity. The present invention also provides methods for identifying agents that bind and/or stimulate TLR and mediate induction of an IRF3 pathway, thereby directing an antimicrobial activity. Additionally, the invention provides methods and agents for suppressing stimulation of TLR, thereby directing an anti-inflammatory response.

Method Of Prevention And Alleviation Of Toxicity By Modulation Of Irf3

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US Patent:
2009018, Jul 16, 2009
Filed:
Oct 4, 2007
Appl. No.:
11/867589
Inventors:
Edward K. Chow - Rancho Palos Verdes CA,
Genhong Cheng - Calabasas CA,
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 31/713
A61K 31/16
A61K 31/715
A61K 31/437
A61K 31/195
A61P 3/00
US Classification:
514 44, 514630, 514 54, 514293, 514562
Abstract:
The invention provides compounds, compositions, animal models, drug screening methods, pharmaceutical compositions, and methods of treatment which relate to the modulation of the metabolism of xenobiotic compounds by administering agents which act on IRF3 or an IRF3 control pathway to modulate the activity, expression, or levels of cytochrome P450 enzymes involved in the metabolism of xenobiotic compounds in a subject.

Polymer Nanofilm Coatings

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US Patent:
2013000, Jan 3, 2013
Filed:
Sep 11, 2012
Appl. No.:
13/609588
Inventors:
Dean Ho - Evanston IL,
Mark Chen - Chicago IL,
Erik Pierstorff - Highland Park IL,
Houjin Huang - Evanston IL,
Edward K. Chow - Rancho Palos Verdes CA,
Genhong Cheng - Calabasas CA,
Assignee:
The Regents of the University of California - Oakland CA
Northwestern University - Evanston IL
International Classification:
A61K 9/70
B32B 27/08
B32B 7/02
B32B 27/28
B82Y 5/00
US Classification:
424443, 428220, 428216, 428141, 977755, 977906
Abstract:
Disclosed herein are nanofilm coatings for implantable medical devices comprising a diblock or triblock copolymer (PEO-PMMA or PMOXA-PDMS-PMOXA, respectively). Such nanofilms, may be used, for example, as amphiphilic supports for therapeutic agents. These materials are conducive towards the formation of active substrates for a suite of biological and medical applications.
Genhong Cheng from Calabasas, CA, age ~56 Get Report